StAR (D10H12) XP ® Rabbit mAb 8449T from Cell Signaling Technology

Product Specs
ItemStAR (D10H12) XP ® Rabbit mAb
CompanyCell Signaling Technology
Price Pricing Info Supplier Page View Company Product Page
Catalog Number8449T
Quantity20 µl
ApplicationsW, IP, IF-IC
ReactivityH, M, R
TargetStAR
IsotypeIgG
HostRabbit
NCBI Full Gene Namesteroidogenic acute regulatory protein
NCBI Gene AliasesSTARD1
ClonalityMonoclonal
Research AreaMetabolism
Molecular Weight28

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Protective role of autophagy in triptolide-induced apoptosis of TM3 Leydig cellsJournal of Translational Internal MedicineSeptember 2, 2023Xiaoyun Ye, Liang Chenmonoclonal antibody (#2983), anti-p-mTOR monoclonal antibody (#5536) , anti-StAR monoclonal antibody (#8449), anti-p70s6k monoclonal antibody(#2708), anti-p-p70s6k monoclonal antibody (#9234) , anti-4E-BP1 monoclonal

(2) Melanocortin 1 receptor regulates cholesterol and bile acid metabolism in the livereLifeJuly 25, 2023Thapa K, Kadiri JJ, Saukkonen K, Pennanen I, Ghimire B, Cai M, Savontaus E, Rinne P.(abcam, #ab103296), MRP4 (Cell Signaling Tech, Frankfurt, DE, #12857), StAR (Cell Signaling Tech, #8449), CYP8B1 (St John’s Laboratory Ltd, #STJ92607), phospho-AMPKα (Cell Signaling Tech, #2535), and AMPKα

(3) ZONAL EXPRESSION OF STARD1 AND OXIDATIVE STRESS IN ALCOHOLIC-RELATED LIVER DISEASEJournal of Lipid ResearchJuly 19, 2023Raquel Fucho, Estel Solsona-Vilarrasa, Sandra Torres, Susana Nuñez, Naroa Insausti-Urkia, Albert Edo, Maria Calvo, Anna Bosch, Gemma Martin, Carlos Enrich, et al.(Santa Cruz, sc292868), OPA1 (Abcam, ab42364), Porin (Merck Millipore, MABN504), StARD1 (Cell Signaling, #8449), β-Actin (Sigma-Aldrich, A3854). Membranes were thoroughly washed with TBS-Tween and incubated for

(4) A spatiotemporal gene expression and cell atlases of the developing rat ovaryCell ProliferationJune 13, 2023Yong Shi, Yanjie Guo, Jiayi Zhou, Guanshen Cui, Jung‐Chien Cheng, Ying Wu, Yong‐Liang Zhao, Lanlan Fang, Xiao Han, Yun‐Gui Yang, et al.using a fluorescence microscope (Nikon). The primary antibodies including rabbit anti‐StAR (1:100, 8449 T, CST), rabbit anti‐FDX1 (1:200, ab109312, Abcam), and rabbit anti‐ALDH1A1 (1:150, PA5‐95937, ThermoFisher).

(5) Synthetic Ionizable Colloidal Drug Aggregates Enable Endosomal DisruptionAdvanced ScienceMay 1, 2023Eric N. Donders, Kai V. Slaughter, Christian Dank, Ahil N. Ganesh, Brian K. Shoichet, Mark Lautens, Molly S. Shoichetfusion was a generous gift from F. Randow.[ 69 ] Viral vector plasmids pCMV‐VSV‐G (8454) and pUMVC (8449) were obtained from Addgene (Teddington, UK) as DH5α stab cultures.[ 70 ] A QIAprep Spin Miniprep

(6) SDNOR, a Novel Antioxidative lncRNA, Is Essential for Maintaining the Normal State and Function of Porcine Follicular Granulosa CellsAntioxidants (Basel, Switzerland)March 24, 2023Huo Y, Li Q, Yang L, Li X, Sun C, Liu Y, Liu H, Pan Z, Li Q, Du X.Sangon, Shanghai, China; 1:1000), anti-CYP19A1 (#A2161, ABclonal, Wuhan, China; 1:1000), anti-StAR (#8449S, Cell Signaling Technology, Shanghai, China; 1:1000), anti-caspase3 (#19677-1-AP, Proteintech, Wuhan,

(7) Mitoguardin2 Is Associated With Hyperandrogenism and Regulates Steroidogenesis in Human Ovarian Granulosa CellsJournal of the Endocrine SocietyMarch 6, 2023Yan MQ, Wang Y, Wang Z, Liu XH, Yang YM, Duan XY, Sun H, Liu XM.monoclonal Anti-LHCGR,AB_2135467,Santa Cruz,sc-25828,WB: 1:50,Mouse monoclonal Anti-StAR,AB_10889737,Cell Signaling Technology,8449,WB: 1:1000; IP: 1:50; IF: 1:100,Rabbit monoclonal Anti-TOMM20,AB_945896,Abcam,ab56783,IF: 1:2000; WB:

(8) SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouseNature communicationsDecember 21, 2022Uchida A, Imaimatsu K, Suzuki H, Han X, Ushioda H, Uemura M, Imura-Kishi K, Hiramatsu R, Takase HM, Hirate Y, et al.rabbit polyclonal anti-SOX9 (Millipore, AB5535, 1:400), rabbit polyclonal anti-STAR (Cell Signaling, 8449, 1:100), rabbit polyclonal anti-VASA/MVH (Abcam, ab13840, 1:10000). The AlexaFluor 488 Tyramide Signal

(9) Oleic acid reduces steroidogenesis by changing the lipid type stored in lipid droplets of ovarian granulosa cellsJournal of Animal Science and BiotechnologyDecember 1, 2022Xiaoge Zhou, Zhaoyi Mo, Yankun Li, Liang Huang, Sihai Yu, Lan Ge, Yamei Hu, Shengjie Shi, Lutong Zhang, Liguang Wang, et al.DGAT2 (Abcam, Shanghai, China), CYP19A1(Abways, Shanghai, China), StAR (Cell Signaling Technology, 8449 T, Danvers, Massachusetts, USA), CYP11A1 (Abways, Shanghai, China) and ACTB (Cwbio, Beijing, China)

(10) A Short Promoter Region Containing Conserved Regulatory Motifs Is Required for Steroidogenic Acute Regulatory Protein (Star) Gene Expression in the Mouse TestisInternational journal of molecular sciencesOctober 9, 2022Bouchard MF, Picard J, Tremblay JJ, Viger RS.available primary antibodies for either a rabbit monoclonal anti-STAR IgG (Cell Signaling Technology Cat# 8449, RRID:AB_10889737) at a dilution of 1:5000 in 5% non-fat dry milk in TBS-T, a mouse monoclonal anti-α-tubulin

(11) Mislocalization of protein kinase A drives pathology in Cushing's syndromeCell reportsJuly 12, 2022Omar MH, Byrne DP, Jones KN, Lakey TM, Collins KB, Lee KS, Daly LA, Forbush KA, Lau HT, Golkowski M, et al.CST 9104 (IF, WB); phospho-PKA Substrate CST 9624 (WB); NeutrAvidin-HRP Pierce 31,030 (WB); StAR CST 8449 (WB); phospho-RIIβ Santa Cruz sc-136460 (WB); RIIβ BD 610626; phospho-ERK1/2 CST 9101 (IF, WB); ERK1/2

(12) Prohibitin-1 plays a regulatory role in Leydig cell steroidogenesisiScienceApril 15, 2022Bassi G, Mishra S.,Cell Signaling Technology,Cat#2426S Anti-PHB2,Cell Signaling Technology,Cat#14085S Anti-StAR,Cell Signaling Technology,Cat#8449S Anti-Cyp11A1,Cell Signaling Technology,Cat#14217S Anti-Total ERK,Cell Signaling Technology,Cat#9102S Anti-Phospho

(13) Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR/cAMP/PKA/StAR pathwayParticle and fibre toxicologyFebruary 17, 2022Jin H, Yan M, Pan C, Liu Z, Sha X, Jiang C, Li L, Pan M, Li D, Han X, et al.(WB) Anti-17β-HSD,Rabbit polyclonal Ab,Proteintech,10978-1-AP,1:1000 (WB) Anti-StAR,Rabbit mAb,Cell Signaling Technology,#8449,1:1000 (WB)1:200 (IF) Anti-LHR,Rabbit polyclonal Ab,Proteintech,19968-1-AP,1:1000 (WB) Specifications

(14) Effect of iodoacetic acid on the reproductive system of male miceFrontiers in pharmacologyJanuary 1, 2022Liang Y, Huang X, Fang L, Wang M, Yu C, Guan Q.and reagents IAA was purchased from Sigma-Aldrich (Shanghai Warehouse, China). Antibodies for STAR (8449s) and CYP11A1 (14217s) were procured from Cell Signaling Technology, Inc. Antibody for CYP17A1 (14447-1-AP)

(15) Restoring Impaired Fertility Through Diet: Observations of Switching From High-Fat Diet During Puberty to Normal Diet in Adulthood Among Obese Male MiceFrontiers in endocrinologyJanuary 1, 2022Qi X, Zhang M, Sun M, Luo D, Guan Q, Yu C.Tris-buffered saline (TBS) for 1 h, and then incubated with specific primary antibodies StAR (1:1000, 8449S, CST), WT-1 (1:1000, 83535S, CST) and DAZL (1:1000, 12633-1-AP, Proteintech) overnight at 4°C. GAPDH

(16) Gigantol Improves Cholesterol Metabolism and Progesterone Biosynthesis in MA-10 Leydig CellsCurrent issues in molecular biologyDecember 23, 2021Basque A, Nguyen HT, Touaibia M, Martin LJ.antibody overnight at 4 °C. Target proteins were detected using a monoclonal anti-StAR (1:1000, Cat.: 8449, Cell Signaling Technology, Danvers, MA, USA), a monoclonal anti-CREB (1:1000, Cat.: 4820, Cell Signaling Technology

(17) In Vitro Analysis of Deoxynivalenol Influence on Steroidogenesis in ProstateToxins (Basel)September 26, 2021Kinga Anna Urbanek, Karolina Kowalska, Dominika Ewa Habrowska-GÃ³rczyÅ„ska, Kamila DomiÅ„ska, Agata Sakowicz, Agnieszka Wanda Piastowska-Ciesielskachemiluminescence detection, the membranes were incubated overnight at 4 °C with primary antibodies: STAR (#8449), CYP11A1 (#14217) (Cell Signaling Technology, Leiden, The Netherlands). Next, the membranes were washed

(18) Kindlin-2 in Sertoli cells is essential for testis development and male fertility in miceCell Death & DiseaseJune 11, 2021Xiaochun Chi et al.concentrations for Western blotting (WB), IF, or IHC analyses as follows: WT1 (SC192; Santa Cruz); StAR (8449; Cell Signaling); TRA98 (ab82527; Abcam); Caspase-3 (9662; Cell Signaling); Ki67 (AF7649; RD system);

(19) Adropin Stimulates Proliferation and Inhibits Adrenocortical Steroidogenesis in the Human Adrenal Carcinoma (HAC15) Cell LineFront Endocrinol (Lausanne)October 8, 2020Ewelina Stelcer et al.primary antibodies: GPR-19 (ab123014, Abcam, UK) (1:200); CYP11B2 (ab167413, Abcam, UK) (1:250); StAR (8449S, Cell Signaling Technology, MA, USA) (1:250); and CYP11A1 (14217S, Cell Signaling Technology, MA, USA)

(20) Kinobead/LC-MS Phosphokinome Profiling Enables Rapid Analyses of Kinase-Dependent Cell Signaling NetworksJournal of Proteome ResearchMarch 6, 2020Martin Golkowski, Venkata Narayana Vidadala, Ho-Tak Lau, Anna Shoemaker, Masami Shimizu-Albergine, Joseph Beavo, Dustin J. Maly, Shao-En Ong#4370), Phospho-PKA Substrate (RRXS*/T*) (100G7E) Rabbit mAb (Cat #9624), StAR (D10H12) Rabbit mAb (Cat #8449) and p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb (Cat #4695). Preparation of optimized kinobead mixture The

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StAR (D10H12) XP ® Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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StAR (D10H12) XP ® Rabbit mAb from Cell Signaling Technology

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